P 22077

CAS No. 1247819-59-5

P 22077 ( P22077; P-22077; P 22077 )

Catalog No. M11000 CAS No. 1247819-59-5

P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 29 In Stock
5MG 47 In Stock
10MG 75 In Stock
25MG 150 In Stock
50MG 287 In Stock
100MG 428 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    P 22077
  • Note
    Research use only, not for human use.
  • Brief Description
    P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.
  • Description
    P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.
  • Synonyms
    P22077; P-22077; P 22077
  • Pathway
    Proteasome/Ubiquitin
  • Target
    DUB
  • Recptor
    USP2; USP4; USP47; USP5; USP7
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1247819-59-5
  • Formula Weight
    315.32
  • Molecular Formula
    C12H7F2NO3S2
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 63 mg/mL (199.79 mM)
  • SMILES
    CC(C1=CC([N+]([O-])=O)=C(SC2=CC=C(F)C=C2F)S1)=O
  • Chemical Name
    1-(5-((2,4-difluorophenyl)thio)-4-nitrothiophen-2-yl)ethanone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tian X, et al. Assay Drug Dev Technol, 2011, 9(2), 165-173.
molnova catalog
related products
  • Ubiquitin Isopeptida...

    A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.

  • Spautin-1

    Spautin-1 is a potent, small molecule inhibitor of autophagy with IC50 of 0.74 uM.

  • XL 188

    XL188 (XL-188) is a potent, selective, non-covalent active-site inhibitor of USP7 with IC50 of 90 nM and 193 nM for USP7 full length enzyme and catalytic domain, respectively.