P 22077
CAS No. 1247819-59-5
P 22077 ( P22077; P-22077; P 22077 )
Catalog No. M11000 CAS No. 1247819-59-5
P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 29 | In Stock |
|
5MG | 47 | In Stock |
|
10MG | 75 | In Stock |
|
25MG | 150 | In Stock |
|
50MG | 287 | In Stock |
|
100MG | 428 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameP 22077
-
NoteResearch use only, not for human use.
-
Brief DescriptionP22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.
-
DescriptionP22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.
-
SynonymsP22077; P-22077; P 22077
-
PathwayProteasome/Ubiquitin
-
TargetDUB
-
RecptorUSP2; USP4; USP47; USP5; USP7
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1247819-59-5
-
Formula Weight315.32
-
Molecular FormulaC12H7F2NO3S2
-
Purity>98%(HPLC)
-
SolubilityDMSO: 63 mg/mL (199.79 mM)
-
SMILESCC(C1=CC([N+]([O-])=O)=C(SC2=CC=C(F)C=C2F)S1)=O
-
Chemical Name1-(5-((2,4-difluorophenyl)thio)-4-nitrothiophen-2-yl)ethanone
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Tian X, et al. Assay Drug Dev Technol, 2011, 9(2), 165-173.
molnova catalog
related products
-
Ubiquitin Isopeptida...
A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.
-
Spautin-1
Spautin-1 is a potent, small molecule inhibitor of autophagy with IC50 of 0.74 uM.
-
XL 188
XL188 (XL-188) is a potent, selective, non-covalent active-site inhibitor of USP7 with IC50 of 90 nM and 193 nM for USP7 full length enzyme and catalytic domain, respectively.